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Genetic and clinical factors predict lithium's effects on PER2 gene expression rhythms in cells from bipolar disorder patients
Bipolar disorder (BD) is associated with abnormal circadian rhythms. In treatment responsive BD patients, lithium (Li) stabilizes mood and reduces suicide risk. Li also affects circadian rhythms and expression of ‘clock genes' that control them. However, the extent to which BD, Li and the circa...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818008/ https://www.ncbi.nlm.nih.gov/pubmed/24150227 http://dx.doi.org/10.1038/tp.2013.90 |