Cargando…

Upregulated dynorphin opioid peptides mediate alcohol-induced learning and memory impairment

The dynorphin opioid peptides control glutamate neurotransmission in the hippocampus. Alcohol-induced dysregulation of this circuit may lead to impairments in spatial learning and memory. This study examines whether changes in the hippocampal dynorphin and glutamate systems are related, and contribu...

Descripción completa

Detalles Bibliográficos
Autores principales: Kuzmin, A, Chefer, V, Bazov, I, Meis, J, Ögren, S O, Shippenberg, T, Bakalkin, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818015/
https://www.ncbi.nlm.nih.gov/pubmed/24105441
http://dx.doi.org/10.1038/tp.2013.72