Cargando…

Upregulated dynorphin opioid peptides mediate alcohol-induced learning and memory impairment

The dynorphin opioid peptides control glutamate neurotransmission in the hippocampus. Alcohol-induced dysregulation of this circuit may lead to impairments in spatial learning and memory. This study examines whether changes in the hippocampal dynorphin and glutamate systems are related, and contribu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kuzmin, A, Chefer, V, Bazov, I, Meis, J, Ögren, S O, Shippenberg, T, Bakalkin, G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818015/ https://www.ncbi.nlm.nih.gov/pubmed/24105441 http://dx.doi.org/10.1038/tp.2013.72

Ejemplares similares

Dynorphin and κ-Opioid Receptor Dysregulation in the Dopaminergic Reward System of Human Alcoholics
por: Bazov, Igor, et al.
Publicado: (2018)

Alcohol-induced plasticity in the dynorphin/kappa-opioid receptor system
por: Sirohi, Sunil, et al.
Publicado: (2012)

Conformation Effects of CpG Methylation on Single-Stranded DNA Oligonucleotides: Analysis of the Opioid Peptide Dynorphin-Coding Sequences
por: Taqi, Malik Mumtaz, et al.
Publicado: (2012)

Downregulation of the endogenous opioid peptides in the dorsal striatum of human alcoholics
por: Sarkisyan, Daniil, et al.
Publicado: (2015)

Downregulation of the neuronal opioid gene expression concomitantly with neuronal decline in dorsolateral prefrontal cortex of human alcoholics
por: Bazov, Igor, et al.
Publicado: (2018)

Compartment-specific opioid receptor signaling is selectively modulated by different dynorphin peptides
por: Kunselman, Jennifer M, et al.
Publicado: (2021)

Epigenetic and Transcriptional Control of the Opioid Prodynorphine Gene: In-Depth Analysis in the Human Brain
por: Nosova, Olga, et al.
Publicado: (2021)

The dynorphin/kappa opioid receptor mediates adverse immunological and behavioral outcomes induced by repetitive blast trauma
por: Lee, Suhjung Janet, et al.
Publicado: (2022)

A non-opioid pathway for dynorphin-caused spinal cord injury in rats☆
por: Chen, Yu, et al.
Publicado: (2012)

Ginsenoside Re protects methamphetamine-induced dopaminergic neurotoxicity in mice via upregulation of dynorphin-mediated κ-opioid receptor and downregulation of substance P-mediated neurokinin 1 receptor
por: Dang, Duy-Khanh, et al.
Publicado: (2018)

Selective Changes of GABA(A) Channel Subunit mRNAs in the Hippocampus and Orbitofrontal Cortex but not in Prefrontal Cortex of Human Alcoholics
por: Jin, Zhe, et al.
Publicado: (2012)

Dynorphin/kappa opioid receptor system regulation on amygdaloid circuitry: Implications for neuropsychiatric disorders
por: Limoges, Aaron, et al.
Publicado: (2022)

Plasma membrane poration by opioid neuropeptides: a possible mechanism of pathological signal transduction
por: Maximyuk, O, et al.
Publicado: (2015)

Improving the Utility of a Dynorphin Peptide Analogue Using Mannosylated Glycoliposomes
por: Lewicky, Jordan D., et al.
Publicado: (2021)

Functional Characterization of Spinocerebellar Ataxia Associated Dynorphin A Mutant Peptides
por: Lieb, Andreas, et al.
Publicado: (2021)

CRF1-R Activation of the Dynorphin/Kappa Opioid System in the Mouse Basolateral Amygdala Mediates Anxiety-Like Behavior
por: Bruchas, Michael R., et al.
Publicado: (2009)

Dynorphin-Kappa Opioid Receptor Signaling Partly Mediates Estrogen Negative Feedback Effect on LH Pulses in Female Rats
por: MOSTARI, Mst. Parvin, et al.
Publicado: (2013)

Expression of specific ionotropic glutamate and GABA-A receptor subunits is decreased in central amygdala of alcoholics
por: Jin, Zhe, et al.
Publicado: (2014)

A Genetic Polymorphism of the Endogenous Opioid Dynorphin Modulates Monetary Reward Anticipation in the Corticostriatal Loop
por: Votinov, Mikhail, et al.
Publicado: (2014)

Traumatic Stress-Induced Vulnerability to Addiction: Critical Role of the Dynorphin/Kappa Opioid Receptor System
por: Leconte, Claire, et al.
Publicado: (2022)

κ Opioid Receptor-Dynorphin Signaling in the Central Amygdala Regulates Conditioned Threat Discrimination and Anxiety
por: Baird, Madison A., et al.
Publicado: (2021)

Design and development of novel, short, stable dynorphin-based opioid agonists for safer analgesic therapy
por: Lohman, Rink-Jan, et al.
Publicado: (2023)

Kappa opioid receptor antagonist and N-methyl-D-aspartate receptor antagonist affect dynorphin-induced spinal cord electrophysiologic impairment☆
por: Chen, Yu, et al.
Publicado: (2012)

GABA-A and NMDA receptor subunit mRNA expression is altered in the caudate but not the putamen of the postmortem brains of alcoholics
por: Bhandage, Amol K., et al.
Publicado: (2014)

Repeated Ethanol Exposure Alters DNA Methylation Status and Dynorphin/Kappa-Opioid Receptor Expression in Nucleus Accumbens of Alcohol-Preferring AA Rats
por: Niinep, Kerly, et al.
Publicado: (2021)

Selective increases of AMPA, NMDA, and kainate receptor subunit mRNAs in the hippocampus and orbitofrontal cortex but not in prefrontal cortex of human alcoholics
por: Jin, Zhe, et al.
Publicado: (2014)

Involvement of dynorphin in anxiogenic effects of estrogen
por: Kastenberger, Iris, et al.
Publicado: (2009)

Modulation of feeding behavior and metabolism by dynorphin
por: Ghule, Aishwarya, et al.
Publicado: (2020)

Discovery of Amphipathic Dynorphin A Analogues to Inhibit the Neuroexcitatory Effects of Dynorphin A through Bradykinin Receptors in the Spinal Cord
por: Lee, Yeon Sun, et al.
Publicado: (2014)

Endogenous dynorphin in emotional control and stress response
por: Schwarzer, Christoph, et al.
Publicado: (2009)

Is On-Demand Dynorphin Destined to Be in Demand to Decrease Seizures?
por: Christian-Hinman, Catherine A.
Publicado: (2020)

The opioid peptide dynorphin A induces leukocyte responses via integrin Mac-1 (α(M)β(2), CD11b/CD18)
por: Podolnikova, Nataly P., et al.
Publicado: (2015)

Big dynorphin is a neuroprotector scaffold against amyloid β-peptide aggregation and cell toxicity
por: Gallego-Villarejo, Lucía, et al.
Publicado: (2022)

Neuroadaptations in Human Chronic Alcoholics: Dysregulation of the NF-κB System
por: Ökvist, Anna, et al.
Publicado: (2007)

Cryo-EM structure of human κ-opioid receptor-G(i) complex bound to an endogenous agonist dynorphin A
por: Chen, Yuxiang, et al.
Publicado: (2022)

Endogenous dynorphin in emotional control and stress response revisited
por: Schwarzer, Christoph, et al.
Publicado: (2010)

Relevance of the Kappa Dynorphin System to Schizophrenia and Its Therapeutics
por: Abi-Dargham, Anissa
Publicado: (2021)

l-DOPA-induced Dyskinesia is Associated with Regional Increase of Striatal Dynorphin Peptides as Elucidated by Imaging Mass Spectrometry
por: Hanrieder, Jörg, et al.
Publicado: (2011)

Distribution and regulation of gonadotropin-releasing hormone, kisspeptin, RF-amide related peptide-3, and dynorphin in the bovine hypothalamus
por: Tanco, Valeria M., et al.
Publicado: (2016)

Dynorphin Activates Quorum Sensing Quinolone Signaling in Pseudomonas aeruginosa
por: Zaborina, Olga, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_5vcjk4ao8afbufohhbo3ngscsq