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Selective Permeabilization of the Blood–Brain Barrier at Sites of Metastasis
BACKGROUND: Effective chemotherapeutics for primary systemic tumors have limited access to brain metastases because of the blood–brain barrier (BBB). The aim of this study was to develop a strategy for specifically permeabilizing the BBB at sites of cerebral metastases. METHODS: BALB/c mice were inj...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818170/ https://www.ncbi.nlm.nih.gov/pubmed/24108809 http://dx.doi.org/10.1093/jnci/djt276 |