Elevated Klotho Promoter Methylation Is Associated with Severity of Chronic Kidney Disease

Klotho (KL) expression is down-regulated in the renal tissues of chronic kidney disease (CKD) animal models and patients with end-stage renal disease. The putative role of KL promoter hypermethylation in the progression of CKD remains unclear. The present study aimed to determine renal and periphera...

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Detalles Bibliográficos
Autores principales: Chen, Jing, Zhang, Xiaoyan, Zhang, Han, Lin, Jing, Zhang, Chen, Wu, Qing, Ding, Xiaoqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818221/
https://www.ncbi.nlm.nih.gov/pubmed/24224012
http://dx.doi.org/10.1371/journal.pone.0079856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818221/
https://www.ncbi.nlm.nih.gov/pubmed/24224012
http://dx.doi.org/10.1371/journal.pone.0079856

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