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Activity of the mitochondrial calcium uniporter varies greatly between tissues

The mitochondrial calcium uniporter (MCU) is a highly selective channel responsible for mitochondrial Ca(2+) uptake. The MCU shapes cytosolic Ca(2+) signals, controls mitochondrial ATP production, and is involved in cell death. Here, using direct patch-clamp recording from the inner mitochondrial me...

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Detalles Bibliográficos
Autores principales: Fieni, Francesca, Lee, Sung Bae, Jan, Yuh Nung, Kirichok, Yuriy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818247/
https://www.ncbi.nlm.nih.gov/pubmed/23271651
http://dx.doi.org/10.1038/ncomms2325