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UNC79 and UNC80, Putative Auxiliary Subunits of the NARROW ABDOMEN Ion Channel, Are Indispensable for Robust Circadian Locomotor Rhythms in Drosophila

In the fruit fly Drosophila melanogaster, a network of circadian pacemaker neurons drives daily rhythms in rest and activity. The ion channel NARROW ABDOMEN (NA), orthologous to the mammalian sodium leak channel NALCN, functions downstream of the molecular circadian clock in pacemaker neurons to pro...

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Detalles Bibliográficos
Autores principales: Lear, Bridget C., Darrah, Eric J., Aldrich, Benjamin T., Gebre, Senetibeb, Scott, Robert L., Nash, Howard A., Allada, Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818319/
https://www.ncbi.nlm.nih.gov/pubmed/24223770
http://dx.doi.org/10.1371/journal.pone.0078147