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Epigenetic Profiles in Children with a Neural Tube Defect; A Case-Control Study in Two Populations
Folate deficiency is implicated in the causation of neural tube defects (NTDs). The preventive effect of periconceptional folic acid supplement use is partially explained by the treatment of a deranged folate-dependent one carbon metabolism, which provides methyl groups for DNA-methylation as an epi...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818348/ https://www.ncbi.nlm.nih.gov/pubmed/24223810 http://dx.doi.org/10.1371/journal.pone.0078462 |