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Epigenetic Profiles in Children with a Neural Tube Defect; A Case-Control Study in Two Populations

Folate deficiency is implicated in the causation of neural tube defects (NTDs). The preventive effect of periconceptional folic acid supplement use is partially explained by the treatment of a deranged folate-dependent one carbon metabolism, which provides methyl groups for DNA-methylation as an epi...

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Detalles Bibliográficos
Autores principales: Stolk, Lisette, Bouwland-Both, Marieke I., van Mill, Nina H., Verbiest, Michael M. P. J., Eilers, Paul H. C., Zhu, Huiping, Suarez, Lucina, Uitterlinden, André G., Steegers-Theunissen, Régine P. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818348/
https://www.ncbi.nlm.nih.gov/pubmed/24223810
http://dx.doi.org/10.1371/journal.pone.0078462