Regulation of Autophagy Via PERK-eIF2α Effectively Relieve the Radiation Myelitis Induced by Iodine-125

Radiation myelitis is the most serious complication in clinical radiotherapy for spinal metastases. We previously showed that (125)I brachytherapy induced apoptosis of spinal cord neurons accompanied by autophagy. In this study, we further investigated the mechanism by which (125)I radiation trigger...

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Detalles Bibliográficos
Autores principales: Yang, Zuozhang, Xu, Yongqing, Xu, Lei, Maccauro, Giulio, Rossi, Barbara, Chen, Yanjin, Li, Hongjun, Zhang, Jing, Sun, Hongpu, Yang, Yihao, Xu, Da, Liu, Xuefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818370/
https://www.ncbi.nlm.nih.gov/pubmed/24223705
http://dx.doi.org/10.1371/journal.pone.0076819

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818370/
https://www.ncbi.nlm.nih.gov/pubmed/24223705
http://dx.doi.org/10.1371/journal.pone.0076819

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