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Fatty Acid Synthase as a Factor Required for Exercise-Induced Cognitive Enhancement and Dentate Gyrus Cellular Proliferation

Voluntary running is a robust inducer of adult hippocampal neurogenesis. Given that fatty acid synthase (FASN), the key enzyme for de novo fatty acid biosynthesis, is critically involved in proliferation of embryonic and adult neural stem cells, we hypothesized that FASN could mediate both exercise-...

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Detalles Bibliográficos
Autores principales: Chorna, Nataliya E., Santos-Soto, Iván J., Carballeira, Nestor M., Morales, Joan L., de la Nuez, Janneliz, Cátala-Valentin, Alma, Chornyy, Anatoliy P., Vázquez-Montes, Adrinel, De Ortiz, Sandra Peña
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818398/
https://www.ncbi.nlm.nih.gov/pubmed/24223732
http://dx.doi.org/10.1371/journal.pone.0077845