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Identification of a Wee1–Like Kinase Gene Essential for Procyclic Trypanosoma brucei Survival

Regulation of eukaryotic cell cycle progression requires sequential activation and inactivation of cyclin-dependent kinases (CDKs). Activation of the cyclin B-cdc2 kinase complex is a pivotal step in mitotic initiation and the tyrosine kinase Wee1 is a key regulator of cell cycle sequence during G2/...

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Detalles Bibliográficos
Autores principales: Boynak, Natalia Y., Rojas, Federico, D’Alessio, Cecilia, Vilchez Larrea, Salomé C., Rodriguez, Vanina, Ghiringhelli, Pablo D., Téllez-Iñón, María T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818516/
https://www.ncbi.nlm.nih.gov/pubmed/24223931
http://dx.doi.org/10.1371/journal.pone.0079364