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Effect of Iboga Alkaloids on µ-Opioid Receptor-Coupled G Protein Activation

OBJECTIVE: The iboga alkaloids are a class of small molecules defined structurally on the basis of a common ibogamine skeleton, some of which modify opioid withdrawal and drug self-administration in humans and preclinical models. These compounds may represent an innovative approach to neurobiologica...

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Detalles Bibliográficos
Autores principales: Antonio, Tamara, Childers, Steven R., Rothman, Richard B., Dersch, Christina M., King, Christine, Kuehne, Martin, Bornmann, William G., Eshleman, Amy J., Janowsky, Aaron, Simon, Eric R., Reith, Maarten E. A., Alper, Kenneth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818563/
https://www.ncbi.nlm.nih.gov/pubmed/24204784
http://dx.doi.org/10.1371/journal.pone.0077262