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Drosophila Ric-8 interacts with the Gα(12/13) subunit, Concertina, during activation of the Folded gastrulation pathway
Heterotrimeric G proteins, composed of α, β, and γ subunits, are activated by exchange of GDP for GTP on the Gα subunit. Canonically, Gα is stimulated by the guanine-nucleotide exchange factor (GEF) activity of ligand-bound G protein–coupled receptors. However, Gα subunits may also be activated in a...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818808/ https://www.ncbi.nlm.nih.gov/pubmed/24006487 http://dx.doi.org/10.1091/mbc.E12-11-0813 |