Structural and Affinity Analyses of G-Quadruplex DNA Aptamers for Camptothecin Derivatives

We recently selected DNA aptamers that bind to camptothecin (CPT) and CPT derivatives from a 70-mer oligodeoxyribonucleotide (ODN) library using the Systematic Evolution of Ligands by EXponential enrichment (SELEX) method. The target-binding activity of the obtained 70-mer CPT-binding DNA aptamer, t...

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Detalles Bibliográficos
Autores principales: Fujita, Hiroto, Imaizumi, Yuri, Kasahara, Yuuya, Kitadume, Shunsuke, Ozaki, Hiroaki, Kuwahara, Masayasu, Sugimoto, Naoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818834/
https://www.ncbi.nlm.nih.gov/pubmed/24276420
http://dx.doi.org/10.3390/ph6091082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818834/
https://www.ncbi.nlm.nih.gov/pubmed/24276420
http://dx.doi.org/10.3390/ph6091082

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