What Goes around Comes around-A Comparative Study of the Influence of Chemical Modifications on the Antimicrobial Properties of Small Cyclic Peptides

Tryptophan and arginine-rich cyclic hexapeptides of the type cyclo-RRRWFW combine high antibacterial activity with rapid cell killing kinetics, but show low toxicity in human cell lines. The peptides fulfil the structural requirements for membrane interaction such as high amphipathicity and cationic...

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Detalles Bibliográficos
Autores principales: Scheinpflug, Kathi, Nikolenko, Heike, Komarov, Igor V., Rautenbach, Marina, Dathe, Margitta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818835/
https://www.ncbi.nlm.nih.gov/pubmed/24276422
http://dx.doi.org/10.3390/ph6091130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818835/
https://www.ncbi.nlm.nih.gov/pubmed/24276422
http://dx.doi.org/10.3390/ph6091130

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