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What Goes around Comes around-A Comparative Study of the Influence of Chemical Modifications on the Antimicrobial Properties of Small Cyclic Peptides
Tryptophan and arginine-rich cyclic hexapeptides of the type cyclo-RRRWFW combine high antibacterial activity with rapid cell killing kinetics, but show low toxicity in human cell lines. The peptides fulfil the structural requirements for membrane interaction such as high amphipathicity and cationic...
Autores principales: | Scheinpflug, Kathi, Nikolenko, Heike, Komarov, Igor V., Rautenbach, Marina, Dathe, Margitta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818835/ https://www.ncbi.nlm.nih.gov/pubmed/24276422 http://dx.doi.org/10.3390/ph6091130 |
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