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Decreased Copper in Alzheimer's Disease Brain Is Predominantly in the Soluble Extractable Fraction

Alzheimer's disease (AD) is the leading cause of dementia and represents a significant burden on the global economy and society. The role of transition metals, in particular copper (Cu), in AD has become of significant interest due to the dyshomeostasis of these essential elements, which can im...

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Detalles Bibliográficos
Autores principales: Rembach, Alan, Hare, Dominic J., Lind, Monica, Fowler, Christopher J., Cherny, Robert A., McLean, Catriona, Bush, Ashley I., Masters, Colin L., Roberts, Blaine R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818847/
https://www.ncbi.nlm.nih.gov/pubmed/24228186
http://dx.doi.org/10.1155/2013/623241