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Deletion of the signalling molecule synthase ScbA has pleiotropic effects on secondary metabolite biosynthesis, morphological differentiation and primary metabolism in Streptomyces coelicolor A3(2)

Streptomycetes have high biotechnological relevance as producers of diverse metabolites widely used in medical and agricultural applications. The biosynthesis of these metabolites is controlled by signalling molecules, γ‐butyrolactones, that act as bacterial hormones. In Streptomyces coelicolor, a g...

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Detalles Bibliográficos
Autores principales: D'Alia, Davide, Eggle, Daniela, Nieselt, Kay, Hu, Wei‐Shou, Breitling, Rainer, Takano, Eriko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818864/
https://www.ncbi.nlm.nih.gov/pubmed/21342469
http://dx.doi.org/10.1111/j.1751-7915.2010.00232.x