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Antistress effect of red ginseng in brain cells is mediated by TACE repression via PADI4

Ginseng is known to have antistress effects. Previously, red ginseng (RG) was shown to repress stress-induced peptidyl arginine deiminase type IV (PADI4) via estrogen receptor β (ERβ) in the brain, thus inhibiting brain cell apoptosis. Moreover, tumor necrosis factor (TNF)-α plays a critical role in...

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Detalles Bibliográficos
Autores principales: Kim, Eun-Hye, Kim, In-Hye, Ha, Jung-Ah, Choi, Kwang-Tae, Pyo, Suhkneung, Rhee, Dong-Kwon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Ginseng 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818958/
https://www.ncbi.nlm.nih.gov/pubmed/24198657
http://dx.doi.org/10.5142/jgr.2013.37.315