High-yield production of functional soluble single-domain antibodies in the cytoplasm of Escherichia coli

BACKGROUND: For their application in the area of diagnosis and therapy, single-domain antibodies (sdAbs) offer multiple advantages over conventional antibodies and fragments thereof in terms of size, stability, solubility, immunogenicity, production costs as well as tumor uptake and blood clearance....

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Detalles Bibliográficos
Autores principales: Zarschler, Kristof, Witecy, Stefanie, Kapplusch, Franz, Foerster, Christian, Stephan, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818982/
https://www.ncbi.nlm.nih.gov/pubmed/24161153
http://dx.doi.org/10.1186/1475-2859-12-97

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818982/
https://www.ncbi.nlm.nih.gov/pubmed/24161153
http://dx.doi.org/10.1186/1475-2859-12-97

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