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High-yield production of functional soluble single-domain antibodies in the cytoplasm of Escherichia coli
BACKGROUND: For their application in the area of diagnosis and therapy, single-domain antibodies (sdAbs) offer multiple advantages over conventional antibodies and fragments thereof in terms of size, stability, solubility, immunogenicity, production costs as well as tumor uptake and blood clearance....
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818982/ https://www.ncbi.nlm.nih.gov/pubmed/24161153 http://dx.doi.org/10.1186/1475-2859-12-97 |