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Chemically linked phage idiotype vaccination in the murine B cell lymphoma 1 model
BACKGROUND: B cell malignancies are characterized by clonal expansion of B cells expressing tumor-specific idiotypes on their surface. These idiotypes are ideal target antigens for an individualized immunotherapy. However, previous idiotype vaccines mostly lacked efficiency due to a low immunogenici...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819179/ https://www.ncbi.nlm.nih.gov/pubmed/24152874 http://dx.doi.org/10.1186/1479-5876-11-267 |