Cargando…

Chemically linked phage idiotype vaccination in the murine B cell lymphoma 1 model

BACKGROUND: B cell malignancies are characterized by clonal expansion of B cells expressing tumor-specific idiotypes on their surface. These idiotypes are ideal target antigens for an individualized immunotherapy. However, previous idiotype vaccines mostly lacked efficiency due to a low immunogenici...

Descripción completa

Detalles Bibliográficos
Autores principales: Roehnisch, Tim, Then, Cornelia, Nagel, Wolfgang, Blumenthal, Christina, Braciak, Todd, Donzeau, Mariel, Böhm, Thomas, Bourquin, Carole, Oduncu, Fuat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819179/
https://www.ncbi.nlm.nih.gov/pubmed/24152874
http://dx.doi.org/10.1186/1479-5876-11-267