Molecular Dynamics Simulations Reveal the HIV-1 Vpu Transmembrane Protein to Form Stable Pentamers

The human immunodeficiency virus type I (HIV-1) Vpu protein is 81 residues long and has two cytoplasmic and one transmembrane (TM) helical domains. The TM domain oligomerizes to form a monovalent cation selective ion channel and facilitates viral release from host cells. Exactly how many TM domains...

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Detalles Bibliográficos
Autores principales: Padhi, Siladitya, Khan, Nabab, Jameel, Shahid, Priyakumar, U. Deva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819244/
https://www.ncbi.nlm.nih.gov/pubmed/24223193
http://dx.doi.org/10.1371/journal.pone.0079779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819244/
https://www.ncbi.nlm.nih.gov/pubmed/24223193
http://dx.doi.org/10.1371/journal.pone.0079779

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