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The Effects of Age and the Expression of SPARC on Extracellular Matrix Production by Cardiac Fibroblasts in 3-D Cultures

Fibrillar collagen is the primary component of the cardiac interstitial extracellular matrix. This extracellular matrix undergoes dramatic changes from birth to adulthood and then into advanced age. As evidence, fibrillar collagen content was compared in sections from neonates, adult, and old hearts...

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Detalles Bibliográficos
Autores principales: Trombetta-eSilva, Jessica, Eadie, Erik P., Zhang, Yuhua, Norris, Russell A., Borg, Thomas K., Bradshaw, Amy D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819255/
https://www.ncbi.nlm.nih.gov/pubmed/24223185
http://dx.doi.org/10.1371/journal.pone.0079715