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Optimal Scaling of Digital Transcriptomes

Deep sequencing of transcriptomes has become an indispensable tool for biology, enabling expression levels for thousands of genes to be compared across multiple samples. Since transcript counts scale with sequencing depth, counts from different samples must be normalized to a common scale prior to c...

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Detalles Bibliográficos
Autores principales: Glusman, Gustavo, Caballero, Juan, Robinson, Max, Kutlu, Burak, Hood, Leroy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819321/
https://www.ncbi.nlm.nih.gov/pubmed/24223126
http://dx.doi.org/10.1371/journal.pone.0077885