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Expression of Estrogen-Related Gene Markers in Breast Cancer Tissue Predicts Aromatase Inhibitor Responsiveness

Aromatase inhibitors (AIs) are the most effective class of drugs in the endocrine treatment of breast cancer, with an approximate 50% treatment response rate. Our objective was to determine whether intratumoral expression levels of estrogen-related genes are predictive of AI responsiveness in postme...

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Detalles Bibliográficos
Autores principales: Moy, Irene, Lin, Zhihong, Rademaker, Alfred W., Reierstad, Scott, Khan, Seema A., Bulun, Serdar E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819361/
https://www.ncbi.nlm.nih.gov/pubmed/24223121
http://dx.doi.org/10.1371/journal.pone.0077543