Dietary Iron Enhances Colonic Inflammation and IL-6/IL-11-Stat3 Signaling Promoting Colonic Tumor Development in Mice

Chronic intestinal inflammation and high dietary iron are associated with colorectal cancer development. The role of Stat3 activation in iron-induced colonic inflammation and tumorigenesis was investigated in a mouse model of inflammation-associated colorectal cancer. Mice, fed either an iron-supple...

Descripción completa

Detalles Bibliográficos
Autores principales: Chua, Anita C. G., Klopcic, Borut R. S., Ho, Desiree S., Fu, S. Kristine, Forrest, Cynthia H., Croft, Kevin D., Olynyk, John K., Lawrance, Ian C., Trinder, Debbie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819375/
https://www.ncbi.nlm.nih.gov/pubmed/24223168
http://dx.doi.org/10.1371/journal.pone.0078850

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819375/
https://www.ncbi.nlm.nih.gov/pubmed/24223168
http://dx.doi.org/10.1371/journal.pone.0078850

Ejemplares similares