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Regulation of Gγ-Globin Gene by ATF2 and Its Associated Proteins through the cAMP-Response Element
The upstream Gγ-globin cAMP-response element (G-CRE) plays an important role in regulating Gγ-globin expression through binding of ATF2 and its DNA-binding partners defined in this study. ATF2 knockdown resulted in a significant reduction of γ-globin expression accompanied by decreased ATF2 binding...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819381/ https://www.ncbi.nlm.nih.gov/pubmed/24223142 http://dx.doi.org/10.1371/journal.pone.0078253 |