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Use of Nonelectrolytes Reveals the Channel Size and Oligomeric Constitution of the Borrelia burgdorferi P66 Porin

In the Lyme disease spirochete Borrelia burgdorferi, the outer membrane protein P66 is capable of pore formation with an atypical high single-channel conductance of 11 nS in 1 M KCl, which suggested that it could have a larger diameter than ‘normal’ Gram-negative bacterial porins. We studied the dia...

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Detalles Bibliográficos
Autores principales: Bárcena-Uribarri, Iván, Thein, Marcus, Maier, Elke, Bonde, Mari, Bergström, Sven, Benz, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819385/
https://www.ncbi.nlm.nih.gov/pubmed/24223145
http://dx.doi.org/10.1371/journal.pone.0078272