Notch-1 Signaling Regulates Microglia Activation via NF-κB Pathway after Hypoxic Exposure In Vivo and In Vitro

Neuroinflammation mediated by the activated microglia is suggested to play a pivotal role in the pathogenesis of hypoxic brain injury; however, the underlying mechanism of microglia activation remains unclear. Here, we show that the canonical Notch signaling orchestrates microglia activation after h...

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Detalles Bibliográficos
Autores principales: Yao, Linli, Kan, Enci Mary, Kaur, Charanjit, Dheen, S. Thameem, Hao, Aijun, Lu, Jia, Ling, Eng-Ang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819391/
https://www.ncbi.nlm.nih.gov/pubmed/24223152
http://dx.doi.org/10.1371/journal.pone.0078439

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819391/
https://www.ncbi.nlm.nih.gov/pubmed/24223152
http://dx.doi.org/10.1371/journal.pone.0078439

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