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Notch-1 Signaling Regulates Microglia Activation via NF-κB Pathway after Hypoxic Exposure In Vivo and In Vitro
Neuroinflammation mediated by the activated microglia is suggested to play a pivotal role in the pathogenesis of hypoxic brain injury; however, the underlying mechanism of microglia activation remains unclear. Here, we show that the canonical Notch signaling orchestrates microglia activation after h...
Autores principales: | Yao, Linli, Kan, Enci Mary, Kaur, Charanjit, Dheen, S. Thameem, Hao, Aijun, Lu, Jia, Ling, Eng-Ang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819391/ https://www.ncbi.nlm.nih.gov/pubmed/24223152 http://dx.doi.org/10.1371/journal.pone.0078439 |
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