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The N-terminal cytoplasmic region of NCBE displays features of an intrinsic disordered structure and represents a novel target for specific drug screening

The sodium dependent bicarbonate transporter NCBE/NBCn2 is predominantly expressed in the central nervous system (CNS). The highest protein concentrations are found in the choroid plexus. The primary function of this integral plasma membrane transport protein is to regulate intracellular neuronal pH...

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Detalles Bibliográficos
Autores principales: Bjerregaard-Andersen, Kaare, Perdreau-Dahl, Harmonie, Guldsten, Hanne, Praetorius, Jeppe, Jensen, Jan K., Morth, Jens P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819638/
https://www.ncbi.nlm.nih.gov/pubmed/24223558
http://dx.doi.org/10.3389/fphys.2013.00320