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Aging is associated with highly defined epigenetic changes in the human epidermis

BACKGROUND: Altered DNA methylation patterns represent an attractive mechanism for understanding the phenotypic changes associated with human aging. Several studies have described global and complex age-related methylation changes, but their structural and functional significance has remained largel...

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Detalles Bibliográficos
Autores principales: Raddatz, Günter, Hagemann, Sabine, Aran, Dvir, Söhle, Jörn, Kulkarni, Pranav P, Kaderali, Lars, Hellman, Asaf, Winnefeld, Marc, Lyko, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819645/
https://www.ncbi.nlm.nih.gov/pubmed/24279375
http://dx.doi.org/10.1186/1756-8935-6-36