Molecular docking studies for the identification of novel melatoninergic inhibitors for acetylserotonin-O-methyltransferase using different docking routines

BACKGROUND: N-Acetylserotonin O-methyltransferase (ASMT) is an enzyme which by converting nor-melatonin to melatonin catalyzes the final reaction in melatonin biosynthesis in tryptophan metabolism pathway. High Expression of ASMT gene is evident in PPTs. The presence of abnormally high levels of ASM...

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Detalles Bibliográficos
Autores principales: Azam, Syed Sikander, Abbasi, Sumra Wajid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819668/
https://www.ncbi.nlm.nih.gov/pubmed/24156411
http://dx.doi.org/10.1186/1742-4682-10-63

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819668/
https://www.ncbi.nlm.nih.gov/pubmed/24156411
http://dx.doi.org/10.1186/1742-4682-10-63

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