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SORBS2 and TLR3 induce premature senescence in primary human fibroblasts and keratinocytes
BACKGROUND: Genetic aberrations are required for the progression of HPV-induced cervical precancers. A prerequisite for clonal expansion of cancer cells is unlimited proliferative capacity. In a cell culture model for cervical carcinogenesis loss of genes located on chromosome 4q35→qter and chromoso...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819711/ https://www.ncbi.nlm.nih.gov/pubmed/24165198 http://dx.doi.org/10.1186/1471-2407-13-507 |