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SORBS2 and TLR3 induce premature senescence in primary human fibroblasts and keratinocytes

BACKGROUND: Genetic aberrations are required for the progression of HPV-induced cervical precancers. A prerequisite for clonal expansion of cancer cells is unlimited proliferative capacity. In a cell culture model for cervical carcinogenesis loss of genes located on chromosome 4q35→qter and chromoso...

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Detalles Bibliográficos
Autores principales:	Liesenfeld, Melanie, Mosig, Sandy, Funke, Harald, Jansen, Lars, Runnebaum, Ingo B, Dürst, Matthias, Backsch, Claudia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819711/ https://www.ncbi.nlm.nih.gov/pubmed/24165198 http://dx.doi.org/10.1186/1471-2407-13-507

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