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Salmonella Typhimurium TTSS-2 deficient mig-14 mutant shows attenuation in immunocompromised mice and offers protection against wild-type Salmonella Typhimurium infection

BACKGROUND: Development of Salmonella enterica serovar Typhimurium (S. Typhimurium) live attenuated vaccine carrier strain to prevent enteric infections has been a subject of intensive study. Several mutants of S. Typhimurium have been proposed as an effective live attenuated vaccine strain. Unfortu...

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Detalles Bibliográficos
Autores principales: Pati, Niladri Bhusan, Vishwakarma, Vikalp, Selvaraj, Sathish kumar, Dash, Sabyasachi, Saha, Bhaskar, Singh, Neera, Suar, Mrutyunjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819739/
https://www.ncbi.nlm.nih.gov/pubmed/24148706
http://dx.doi.org/10.1186/1471-2180-13-236