Molecular co-evolution of a protease and its substrate elucidated by analysis of the activity of predicted ancestral hatching enzyme

BACKGROUND: Hatching enzyme is a protease that digests the egg envelope, enabling hatching of the embryo. We have comprehensively studied the molecular mechanisms of the enzyme action to its substrate egg envelope, and determined the gene/protein structure and phylogenetic relationships. Because the...

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Detalles Bibliográficos
Autores principales: Kawaguchi, Mari, Inoue, Koji, Iuchi, Ichiro, Nishida, Mutsumi, Yasumasu, Shigeki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819744/
https://www.ncbi.nlm.nih.gov/pubmed/24161109
http://dx.doi.org/10.1186/1471-2148-13-231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819744/
https://www.ncbi.nlm.nih.gov/pubmed/24161109
http://dx.doi.org/10.1186/1471-2148-13-231

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