Avoiding chromosome pathology when replication forks collide

Chromosome duplication normally initiates via the assembly of replication fork complexes at defined origins(1,2). DNA synthesis by any one fork is thought to cease when it meets another travelling in the opposite direction, at which stage the replication machinery may simply dissociate before the na...

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Detalles Bibliográficos
Autores principales: Rudolph, Christian J., Upton, Amy L., Stockum, Anna, Nieduszynski, Conrad A., Lloyd, Robert G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819906/
https://www.ncbi.nlm.nih.gov/pubmed/23892781
http://dx.doi.org/10.1038/nature12312

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819906/
https://www.ncbi.nlm.nih.gov/pubmed/23892781
http://dx.doi.org/10.1038/nature12312

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