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Avoiding chromosome pathology when replication forks collide
Chromosome duplication normally initiates via the assembly of replication fork complexes at defined origins(1,2). DNA synthesis by any one fork is thought to cease when it meets another travelling in the opposite direction, at which stage the replication machinery may simply dissociate before the na...
Autores principales: | Rudolph, Christian J., Upton, Amy L., Stockum, Anna, Nieduszynski, Conrad A., Lloyd, Robert G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819906/ https://www.ncbi.nlm.nih.gov/pubmed/23892781 http://dx.doi.org/10.1038/nature12312 |
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