Grading amino acid properties increased accuracies of single point mutation on protein stability prediction

BACKGROUND: Protein stabilities can be affected sometimes by point mutations introduced to the protein. Current sequence-information-based protein stability prediction encoding schemes of machine learning approaches include sparse encoding and amino acid property encoding. Property encoding schemes...

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Detalles Bibliográficos
Autores principales: Liu, Jianguo, Kang, Xianjiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820156/
https://www.ncbi.nlm.nih.gov/pubmed/22435732
http://dx.doi.org/10.1186/1471-2105-13-44

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820156/
https://www.ncbi.nlm.nih.gov/pubmed/22435732
http://dx.doi.org/10.1186/1471-2105-13-44

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