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Grading amino acid properties increased accuracies of single point mutation on protein stability prediction
BACKGROUND: Protein stabilities can be affected sometimes by point mutations introduced to the protein. Current sequence-information-based protein stability prediction encoding schemes of machine learning approaches include sparse encoding and amino acid property encoding. Property encoding schemes...
Autores principales: | Liu, Jianguo, Kang, Xianjiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820156/ https://www.ncbi.nlm.nih.gov/pubmed/22435732 http://dx.doi.org/10.1186/1471-2105-13-44 |
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