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A gene signature based method for identifying subtypes and subtype-specific drivers in cancer with an application to medulloblastoma
BACKGROUND: Subtypes are widely found in cancer. They are characterized with different behaviors in clinical and molecular profiles, such as survival rates, gene signature and copy number aberrations (CNAs). While cancer is generally believed to have been caused by genetic aberrations, the number of...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820164/ https://www.ncbi.nlm.nih.gov/pubmed/24564171 http://dx.doi.org/10.1186/1471-2105-14-S18-S1 |