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A mouse model of pathological small intestinal epithelial cell apoptosis and shedding induced by systemic administration of lipopolysaccharide

The gut barrier, composed of a single layer of intestinal epithelial cells (IECs) held together by tight junctions, prevents the entrance of harmful microorganisms, antigens and toxins from the gut lumen into the blood. Small intestinal homeostasis is normally maintained by the rate of shedding of s...

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Detalles Bibliográficos
Autores principales: Williams, Jonathan M., Duckworth, Carrie A., Watson, Alastair J. M., Frey, Mark R., Miguel, Jennifer C., Burkitt, Michael D., Sutton, Robert, Hughes, Kevin R., Hall, Lindsay J., Caamaño, Jorge H., Campbell, Barry J., Pritchard, D. Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820262/
https://www.ncbi.nlm.nih.gov/pubmed/24046352
http://dx.doi.org/10.1242/dmm.013284