Cargando…
A mouse model of pathological small intestinal epithelial cell apoptosis and shedding induced by systemic administration of lipopolysaccharide
The gut barrier, composed of a single layer of intestinal epithelial cells (IECs) held together by tight junctions, prevents the entrance of harmful microorganisms, antigens and toxins from the gut lumen into the blood. Small intestinal homeostasis is normally maintained by the rate of shedding of s...
Autores principales: | Williams, Jonathan M., Duckworth, Carrie A., Watson, Alastair J. M., Frey, Mark R., Miguel, Jennifer C., Burkitt, Michael D., Sutton, Robert, Hughes, Kevin R., Hall, Lindsay J., Caamaño, Jorge H., Campbell, Barry J., Pritchard, D. Mark |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Limited
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820262/ https://www.ncbi.nlm.nih.gov/pubmed/24046352 http://dx.doi.org/10.1242/dmm.013284 |
Ejemplares similares
-
Epithelial Cell Shedding and Barrier Function: A Matter of Life and Death at the Small Intestinal Villus Tip
por: Williams, J. M., et al.
Publicado: (2015) -
Author Correction: Mice lacking NF-κB1 exhibit marked DNA damage responses and more severe gastric pathology in response to intraperitoneal tamoxifen administration
por: Burkitt, M. D., et al.
Publicado: (2019) -
Long-Term Iron Deficiency and Dietary Iron Excess Exacerbate Acute Dextran Sodium Sulphate-Induced Colitis and Are Associated with Significant Dysbiosis
por: Mahalhal, Awad, et al.
Publicado: (2021) -
Helicobacter pylori-induced gastric pathology: insights from in vivo and ex vivo models
por: Burkitt, Michael D., et al.
Publicado: (2017) -
NF-κB2 signalling in enteroids modulates enterocyte responses to secreted factors from bone marrow-derived dendritic cells
por: Jones, Lauren G., et al.
Publicado: (2019)