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Fragile X mental retardation protein regulates trans-synaptic signaling in Drosophila

Fragile X syndrome (FXS), the most common inherited determinant of intellectual disability and autism spectrum disorders, is caused by loss of the fragile X mental retardation 1 (FMR1) gene product (FMRP), an mRNA-binding translational repressor. A number of conserved FMRP targets have been identifi...

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Detalles Bibliográficos
Autores principales: Friedman, Samuel H., Dani, Neil, Rushton, Emma, Broadie, Kendal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820263/
https://www.ncbi.nlm.nih.gov/pubmed/24046358
http://dx.doi.org/10.1242/dmm.012229