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SKIP Downregulation Increases TGF-β1-Induced Matrix Metalloproteinase-9 Production in Transformed Keratinocytes

Transforming growth factor-beta (TGF-β1) is a potent inductor of matrix metalloproteinase-9 (MMP-9) in transformed cells. Recently, Ski-interacting protein (SKIP) has been described as a regulator of TGF-β1 signal transduction, but its role in the induction of cell malignance by TGF-β1 has not been...

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Detalles Bibliográficos
Autores principales: Kocić, Jelena, Villar, Victor, Krstić, Aleksandra, Santibanez, Juan F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820466/
https://www.ncbi.nlm.nih.gov/pubmed/24278749
http://dx.doi.org/10.6064/2012/861647