Catalysis of Protein Folding by Chaperones Accelerates Evolutionary Dynamics in Adapting Cell Populations

Although molecular chaperones are essential components of protein homeostatic machinery, their mechanism of action and impact on adaptation and evolutionary dynamics remain controversial. Here we developed a physics-based ab initio multi-scale model of a living cell for population dynamics simulatio...

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Detalles Bibliográficos
Autores principales: Çetinbaş, Murat, Shakhnovich, Eugene I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820506/
https://www.ncbi.nlm.nih.gov/pubmed/24244114
http://dx.doi.org/10.1371/journal.pcbi.1003269

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820506/
https://www.ncbi.nlm.nih.gov/pubmed/24244114
http://dx.doi.org/10.1371/journal.pcbi.1003269

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