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Systematically Differentiating Functions for Alternatively Spliced Isoforms through Integrating RNA-seq Data

Integrating large-scale functional genomic data has significantly accelerated our understanding of gene functions. However, no algorithm has been developed to differentiate functions for isoforms of the same gene using high-throughput genomic data. This is because standard supervised learning requir...

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Detalles Bibliográficos
Autores principales: Eksi, Ridvan, Li, Hong-Dong, Menon, Rajasree, Wen, Yuchen, Omenn, Gilbert S., Kretzler, Matthias, Guan, Yuanfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820534/
https://www.ncbi.nlm.nih.gov/pubmed/24244129
http://dx.doi.org/10.1371/journal.pcbi.1003314