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Dicer Expression Exhibits a Tissue-Specific Diurnal Pattern That Is Lost during Aging and in Diabetes

Dysregulation of circadian rhythmicity is identified as a key factor in disease pathogenesis. Circadian rhythmicity is controlled at both a transcriptional and post-transcriptional level suggesting the role of microRNA (miRNA) and double-stranded RNA (dsRNA) in this process. Endonuclease Dicer contr...

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Detalles Bibliográficos
Autores principales: Yan, Yuanqing, Salazar, Tatiana E., Dominguez, James M., Nguyen, Dung V., Li Calzi, Sergio, Bhatwadekar, Ashay D., Qi, Xiaoping, Busik, Julia V., Boulton, Michael E., Grant, Maria B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820540/
https://www.ncbi.nlm.nih.gov/pubmed/24244599
http://dx.doi.org/10.1371/journal.pone.0080029